Russian missiles struck a city in central Ukraine Thursday, killed 21 people and wounding about 90 more, Ukrainian authorities said. The country's president called the attack "an open act of terrorism" against civilians in locations without any military value.

Ukraine's national police said three missiles hit an office building and damaged nearby residential buildings in Vinnytsia, which is about 167 miles southwest of the capital, Kyiv.

The missile strike ignited a fire that expanded to engulf 50 cars in an adjacent parking lot. The governor of the Vinnytsia region, Serhiy Borzov, said Ukrainian air defense systems shot down another four missiles over the area.

Ukrainian Interior Minister Denys Monastyrskyi told news reporters in Vinnytsya that 21 people were killed in the strike and at least 91 others wounded, 50 of them seriously. He said three children were among the dead.

Ukrainian President Volodymyr Zelenskyy suggested the attack was deliberately aimed at civilians. The strike happened as government officials from about 40 countries met in The Hague to discuss coordinating efforts to investigate and prosecute potential war crimes in Ukraine.

"Every day Russia is destroying the civilian population, killing Ukrainian children, directing missiles at civilian objects. Where there is no military (targets). What is it if not an open act of terrorism?" Zelenskyy wrote on the Telegram messaging app.

Speaking Thursday to CBS News senior foreign correspondent Holly Williams, Ukraine's Minister of Defense Oleksii Reznikov echoed Zelenskyy's remarks, calling the strike in Vinnytsia "the next proof that we have again a war not with a normal state, but we have a war with a state of terrorists."

"They are using their weapons against civilian people, against civilian facilities," the defense chief told CBS News. "You saw the Kremenchuk tragedy, you saw the atrocities in Bucha, Irpin, and again you saw it in Vinnytsia."

Russia didn't officially confirm the strike, but Margarita Simonyan, head of the state-controlled Russian television network RT, said on her Telegram channel that military officials told her a building in Vinnytsia was targeted because it housed Ukrainian "Nazis."

Before the missiles hit Vinnytsia the president's office reported the deaths of five civilians and the wounding of another eight in Russian attacks over the past day. One person was wounded when a missile damaged several buildings in the southern city of Mykolaiv early Thursday, Ukrainian authorities said. A missile attack on Wednesday killed at least five people in the city.

Russian forces also continued artillery and missile attacks in eastern Ukraine, primarily in Donetsk province after overtaking adjacent Luhansk. The city of Lysychansk, the last major stronghold of Ukrainian resistance in Luhansk, fell to Russian forces at the beginning of the month.

Luhansk and Donetsk together make up the Donbas, a mostly Russian-speaking region of steel factories, mines and other industries.

Donetsk Gov. Pavlo Kyrylenko urged residents to evacuate as "quickly as possible."

"We are urging civilians to leave the region, where electricity, water and gas are in short supply after the Russian shelling," Kyrylenko said in televised remarks. "The fighting is intensifying, and people should stop risking their lives and leave the region."

The British Defense Ministry said Thursday that despite continued shelling in the Donbas region, Russian forces did not make major territorial gains in recent days.

"The aging vehicles, weapons and Soviet-era tactics used by Russian forces do not lend themselves to quickly regaining or building momentum unless used in overwhelming mass — which Russia is currently unable to bring to bear," the British ministry said.

Both the Russian forces and Ukrainian militaries are seeking to replenish their depleted stocks of unmanned aerial vehicles to pinpoint enemy positions and guide artillery strikes.

Both sides are looking to procure jamming-resistant, advanced drones that could offer a decisive edge in battle. Ukrainian officials say the demand for such technology is "immense" with crowdfunding efforts underway to raise the necessary cash for purchases.

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